Polynucleotide Injections in London: Consultant-Led Skin Repair & Regeneration at Skinhorizon Clinic

At Skinhorizon Clinic Maida Vale, Polynucleotide injections are redefining skin rejuvenation in London. These next-generation bio-regenerative treatments go beyond hydration — they actively repair cellular damage, improve elasticity, and restore radiance from within. Under the care of Consultant Dermatologist Dr Mohammad Ghazavi, Skinhorizon delivers scientifically proven results through safe, evidence-based aesthetic medicine.

What Are Polynucleotide Injections?

Polynucleotides (PNs) are purified DNA molecules that stimulate cellular repair, improve microcirculation, and enhance skin elasticity. Originally used in medical tissue regeneration, they are now one of dermatology’s most exciting innovations — offering natural, science-backed rejuvenation without adding volume or altering facial contours.

How Do Polynucleotides Work?

Polynucleotides act as biological “messengers” that restore skin health by stimulating fibroblast activity and boosting collagen, elastin, and hyaluronic acid production. They also have antioxidant and anti-inflammatory properties, improving cell turnover and protecting against oxidative stress. The result? Skin that’s stronger, more hydrated, and visibly rejuvenated.

Top Concerns Treated with Polynucleotide Injections

• Fine lines and early wrinkles
• Under-eye hollowness or dark circles (Under-Eye Rejuvenation)
• Skin laxity and dullness
• Sun damage and texture irregularities
• Post-inflammatory pigmentation or scarring (Acne Scars Treatment)

Consultant-Led Approach at Skinhorizon Clinic

At Skinhorizon, all treatments are performed or overseen by Dr Mohammad Ghazavi, Consultant Dermatologist and Fellow of the Royal College of Physicians. With deep expertise in aesthetic dermatology, Dr Ghazavi ensures each Polynucleotide protocol is evidence-based, anatomically precise, and tailored to your individual skin needs.

Our clinical approach integrates PN therapy with advanced modalities like Exosome Therapy, Profhilo® Bio-Remodelling, or Endolift® Laser to achieve comprehensive rejuvenation and repair.

Polynucleotide Treatment Process

1. Consultation & Assessment: Skin analysis and treatment planning with the consultant.
2. Preparation: Cleansing and topical anaesthetic if required.
3. Injection Phase: PNs are injected into targeted layers of the dermis using fine microinjections.
4. Aftercare: Gentle post-care instructions and optional LED Phototherapy to enhance healing.

Results & Downtime

Results develop gradually as the skin regenerates over 3–6 weeks. Patients report improved hydration, tighter texture, and smoother tone after just one session, with optimal effects after 2–3 treatments. Downtime is minimal — most people resume normal activities the same day with only mild redness or swelling.

Polynucleotides vs. Profhilo®

Both Profhilo® and Polynucleotides are injectable skin boosters, but they work differently. Profhilo hydrates and bio-remodels through high-concentration hyaluronic acid, while Polynucleotides actively repair tissue at a cellular level. For many patients, a combination of both delivers superior hydration and structural regeneration.

Can Polynucleotides Be Used Under the Eyes?

Yes. Polynucleotide-based injectables such as PN Eye or Rejuran® are ideal for delicate areas like the under-eye region. They help improve skin thickness, reduce dark circles, and smooth fine lines — without the puffiness or heaviness that fillers can sometimes cause.

Why Choose Skinhorizon Clinic?

• Led by Consultant Dermatologist with 15+ years’ experience
• Medical-grade Polynucleotide formulations
• Evidence-based, CQC-regulated clinic environment
• Customised bio-regeneration plans integrating PN, Profhilo®, or Exosomes
• Trusted by patients across Central and West London

Frequently Asked Questions